CLOZAPINE N-OXIDE

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Clozapine N-oxide is a major metabolite of clozapine that can be detected in the earliest excretion time interval after clozapine administration.

Clozapine N-oxide is a major metabolite of clozapine that can be detected in the earliest excretion time interval after clozapine administration. It is produced by the action of cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4, whose activities, in turn, can be affected by drugs and disease. Clozapine N-oxide is normally biologically inactive. However, it can be used in designer receptor exclusively activated by designer drugs, also known as DREADDs, technology to modulate synthetic receptors in vivo.

Clozapine N-oxide

Others

Other Targets

Others

Neurological Disease

——

34233-69-7

342.82

C18H19ClN4O

98%

DMSO : ≥ 100 mg/mL 291.70 mM; Methanol : ≥ 28.6 mg/mL 83.43 mM H2O : 1 mg/mL2.92 mM;

Clc1ccc2Nc4ccccc4C(=Nc2c1)N3CC[N+]([O-])(C)CC3

3-Chloro-6-(4-methyl-4-oxidopiperazin-4-ium-1-yl)-5H-benzo[b][1,4]benzodiazepine

(-20℃)

With Ice Pack

≥ 2 years