
CLOZAPINE N-OXIDE
CAS No. 34233-69-7
CLOZAPINE N-OXIDE ( Clozapine N-oxide )
产品货号. M18447 CAS No. 34233-69-7
氯氮平 N-氧化物是氯氮平的主要代谢物,可在氯氮平给药后最早的排泄时间间隔内检测到。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥243 | 有现货 |
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5MG | ¥365 | 有现货 |
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10MG | ¥616 | 有现货 |
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25MG | ¥1021 | 有现货 |
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50MG | ¥1515 | 有现货 |
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100MG | ¥2252 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称CLOZAPINE N-OXIDE
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述氯氮平 N-氧化物是氯氮平的主要代谢物,可在氯氮平给药后最早的排泄时间间隔内检测到。
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产品描述Clozapine N-oxide is a major metabolite of clozapine that can be detected in the earliest excretion time interval after clozapine administration. It is produced by the action of cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4, whose activities, in turn, can be affected by drugs and disease. Clozapine N-oxide is normally biologically inactive. However, it can be used in designer receptor exclusively activated by designer drugs, also known as DREADDs, technology to modulate synthetic receptors in vivo.
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体外实验——
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体内实验——
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同义词Clozapine N-oxide
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通路Others
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靶点Other Targets
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受体Others
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研究领域Neurological Disease
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适应症——
化学信息
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CAS Number34233-69-7
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分子量342.82
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分子式C18H19ClN4O
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纯度>98% (HPLC)
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溶解度DMSO : ≥ 100 mg/mL 291.70 mM; Methanol : ≥ 28.6 mg/mL 83.43 mM H2O : 1 mg/mL 2.92 mM
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SMILESClc1ccc2Nc4ccccc4C(=Nc2c1)N3CC[N+]([O-])(C)CC3
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化学全称3-Chloro-6-(4-methyl-4-oxidopiperazin-4-ium-1-yl)-5H-benzo[b][1,4]benzodiazepine
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Dain, J.G., et al. Biotransformation of clozapine in humans. Drug Metabolism and Disposition 25(5), 603-609 (1997).
产品手册




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